RNDr. Petr Šimek, CSc.
Funkce: Vědecký pracovník - Laboratoř analytické biochemie a metabolomiky
Telefon:
+420 387775286 +420 723 648 892
E-mail:
simek@bclab.eu
Web:
www.bclab.eu
Analytická chemie a biochemie biologicky aktivních látek, profilování metabolitů, metabolomické přístupy|Analytical chemistry and biochemistry of biol. active compounds, metabolite profiling, metabolomic approaches
| Celkem nalezeno: 274 záznamů
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| Delawská K., Hájek J., Voráčová K., Kuzma M., Mareš J., Vicková K., Kádek A., Tučková D., Gallob F., Divoká P., Moos M., Opekar S., Koch L., Saurav K., Sedlák D., et al., Šimek P., Villunger A. , Hrouzek P. (2024) Discovery of nostatin A, an azole-containing proteusin with prominent cytostatic and pro-apoptotic aktivity. Organic & Biomolecular Chemistry Early View : DOI: 10.1039/d4ob01395f |
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Gurung K., Šimek P.,
Jegorov A., Palatinus L. (2024) Structure and absolute configuration of natural fungal product beauveriolide I, isolated from Cordyceps javanica, determined by 3D electron diffraction. Acta Crystallographica Section C: Structural Chemistry
80
: 56-61. DOI: 10.1107/S2053229624001359 |
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Kazek M., Chodáková L., Lehr K., Strych L., Nedbalová P., McMullen E., Bajgar A.,
Opekar S., Šimek P.,
Moos M., Doležal T. (2024) Glucose and trehalose metabolism through the cyclic pentose phosphate pathway shapes pathogen resistance and host protection in Drosophila. PLoS Biology
22
: article number: e3002299. DOI: 10.1371/ journal.pbio.3002299 |
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Lásko Z., Hájek T., Jirásko R., Peterka O., Šimek P., Schoenmakers P.J., Holcapek M. (2024) Four-Dimensional Lipidomic Analysis Using Comprehensive Online UHPLC × UHPSFC/Tandem Mass Spectrometry. Analytical Chemistry
96
: 19439-19446. DOI: 10.1021/acs.analchem.4c03946 |
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Marešová L.,
Moos M.,
Opekar S., Kazek M., Eichler C., Šimek P. (2024) A validated HPLC-MS/MS method for the simultaneous determination of ecdysteroid hormones in subminimal amounts of biological material. Journal of Lipid Research
65
: article number: 100640. DOI: 10.1016/j.jlr.2024.100640 |
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Skotnicová P., Srivastava A., Aggarwal D., Talbot J.,
Karlínová I.,
Moos M., Mareš J., Bučinská L., Koník P., Šimek P., Tichý M., Sobotka R. (2024) A thylakoid biogenesis BtpA protein is required for the initial step of tetrapyrrole biosynthesis in cyanobacteria. New Phytologist
241
: 1236–1249. DOI: 10.1111/nph.19397 |
| Jegorov A., Šimek P., Satke J. (2023) Kmen entomopatogenní houby Beauveria pseudobassiana CCM 9191 a použití tohoto kmene jako bioinsekticidu proti lýkožroutu smrkovému a/nebo lýkožroutu severskému. PATENT č. 309914 |
| Jegorov A., Šimek P., Satke J. (2023) Způsob zamezení šíření kůrovce lesním porostem. PATENT č. 309915 |
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Kiss É., Talbot J., Adams N.B.P.,
Opekar S.,
Moos M., Pilný J., Kvasov T., Schneider E., Konik P., Šimek P., Sobotka R. (2023) Chlorophyll biosynthesis under the control of arginine metabolism. Cell Reports
42
: article number: 113265. DOI: 10.1016/j.celrep.2023.113265 |
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Ribeiro J., Hartmann D., Bartošová-Sojková P., Debat H.,
Moos M., Fara J., Šimek P., Palus M., Kučera M., Hajdušek O., Sojka D., Kopáček P., Perner J. (2023) Blood-feeding adaptations and virome assessment of the poultry red mite Dermanyssus gallinae guided by RNA-seq Communications Biology
6
: 517. DOI: 10.1038/s42003-023-04907-x |
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Taleva G., Husová M., Panicucci B., Hierro-Yap C., Pineda E., Biran M.,
Moos M., Butter F., Šimek P., Bringaud F., Panicucci Zíková A. (2023) Mitochondrion of the Trypanosoma brucei long slender bloodstream form is capable of ATP production by substrate-level phosphorylation PLoS pathogens
19
: e1011699. DOI: 10.1371/journal.ppat.1011699 |
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Hůla P.,
Moos M.,
Des Marteaux L. E., Šimek P.,
Košťál V. (2022) Insect cross-tolerance to freezing and drought stress: role of metabolic re-arrangement. Proceedings of the Royal Society B
289
: 20220308. DOI: 10.1098/rspb.2022.0308 |
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Kučera L.,
Moos M.,
Štětina T.,
Korbelová J.,
Vodrážka P.,
Des Marteaux L. E.,
Grgac R.,
Hůla P.,
Rozsypal J., Faltus M., Šimek P., Sedlacek R.,
Košťál V. (2022) A mixture of innate cryoprotectants is key for freeze tolerance and cryopreservation of a drosophilid fly larva. Journal of Experimental Biology
225
: jeb243934. DOI: 10.1242/jeb.243934 |
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Moos M.,
Korbelová J.,
Štětina T.,
Opekar S., Šimek P.,
Grgac R.,
Košťál V. (2022) Cryoprotective metabolites are sourced from both external diet and internal macromolecular reserves during metabolic reprogramming for freeze tolerance in drosophilid fly, Chymomyza costata. Metabolites
12
: 163. DOI: 10.3390/metabo12020163 |
| Šimek P., Jegorov A., Satke J. (2022) Vzorky kultivaru houby C. javanica, kmen CCM8917 jako zdroje cenných látek a doplňku stravy. FUNKČNÍ VZOREK. |
| Šimek P., Satke J., Jegorov A. (2022) Biologický boj s kůrovci a klikorohy pomocí entomopatogenních hub. Vývoj biotechnologie a její aplikace pro obnovení rovnováhy v lesních ekosystémech. OVĚŘENÁ TECHNOLOGIE |
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Vrba P.,
Sucháčková Bartoňová A., Andres M.,
Nedvěd O., Šimek P.,
Konvička M. (2022) Exploring cold hardiness within a butterfly clade: supercooling ability and polyol profiles in European Satyrinae. Insects
13
: article number: 369. DOI: 10.3390/insects13040369 |
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Zahradníčková H.,
Opekar S.,
Řimnáčová L., Šimek P.,
Moos M. (2022) Chiral secondary amino acids, their importance, and methods of analysis. Amino Acids
54
: 687-719. DOI: 10.1007/s00726-022-03136-6 |
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Gäde G., Šimek P., Marco H. (2021) Biochemically identified neuropeptides in a caddisfly (Trichoptera) and a pygmy mole cricket (Orthoptera: Caelifera: Tridactyloidea). Archives of Insect Biochemistry & Physiology
106
: e21778. DOI: 10.1002/arch.21778 |
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Gerber L., Kresse J.-C., Šimek P.,
Berková P., Overgaard J. (2021) Cold acclimation preserves hindgut reabsorption capacity at low temperature in a chill-susceptible insect, Locusta migratoria. Comparative Biochemistry and Physiology, Part A
252
: article number: 110850. DOI: 10.1016/j.cbpa.2020.110850 |
